![]() ![]() 6, 7, 8, 9 Recently, VED therapy has become the second most commonly used modality for penile rehabilitation. Numerous publications have suggested that VED therapy improves erectile function in 84%–95% of patients. Vacuum erectile device (VED) therapy utilizes negative pressure to distend the corporal sinusoids and to increase blood inflow to the penis. 5 evaluated penile length 3 months after RP in a prospective study and found a significant decrease in the flaccid, stretched and circumferential measurements of the penis. 4 showed that the stretched penile length decreases after RP at 3 months of follow-up in most men 48% had considerable shortening greater than 1.0 cm. The most substantial change occurred between the first 4 and 8 months postoperatively. The flaccid and erect measurements of length and circumference decreased 8% and 9%, respectively, after surgery. 3 reported that there was a decrease in all penile dimensions after nerve-sparing RP. 2 Many patients suffer from erectile dysfunction (ED) and penile shrinkage after RP. The beneficial effect of VED therapy is related to antihypoxia by increasing cavernous blood SO 2.Ĭurrently, prostate cancer is the most common solid organ cancer in men, 1 and radical prostatectomy (RP) is a commonly used surgical treatment for localized prostate cancer. These findings suggest that VED therapy can effectively preserve penile size in rats with BCNC injury. The calculated blood constructs in the corpus cavernosum right after VED application were 62% arterial and 38% venous blood. The results showed that VED therapy is effective in preventing penile shrinkage induced by BCNC (Penile shortening: BCNC group 1.9☑.1 mm VED group 0.3☑.0 mm P<0.01. SO 2 values were tested by the blood gas analyzer. After 4 weeks of therapy, the penile blood was extracted by three methods for blood gas analysis (BGA): method 1, cavernous blood was aspirated at the flaccid state method 2, cavernous blood was aspirated at the traction state and method 3, cavernous blood was aspirated immediately after applying VED. Penile length and diameter were measured on a weekly basis. Thirty adult Sprague–Dawley rats were randomly assigned into three groups: group 1, sham surgery group 2, BCNC and group 3, BCNC+VED. ![]() This study was designed to explore the mechanism of VED in penile rehabilitation by analyzing cavernous oxygen saturation (SO 2) and to examine the effect of VED therapy on preventing penile shrinkage after BCNC. Our previous study showed that vacuum erectile device (VED) therapy has improved erectile function in rats with bilateral cavernous nerve crush (BCNC) injuries.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |